Epigenetic disruption of miR-130a promotes prostate cancer by targeting SEC23B and DEPDC1

MicroRNAs (miRNAs) are small, non-coding RNAs that mediate post-transcriptional gene silencing, fine tuning gene expression. In an initial screen, miRNAs were found to be globally down-regulated in prostate cancer (PCa) cell lines and primary tumors. Exposure of PCa cell lines to a demethylating age...

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Bibliographic Details
Main Author: Ramalho-Carvalho, João (author)
Other Authors: Martins, João Barbosa (author), Cekaite, Lina (author), Sveen, Anita (author), Torres-Ferreira, Jorge (author), Pinho dos Santos Graça, Maria Inês (author), Costa-Pinheiro, Pedro (author), Eilertsen, Ina Andrassy (author), Antunes, Luís (author), Oliveira, Jorge (author), Lothe, Ragnhild A. (author), Henrique, Rui (author), Jerónimo, Carmen (author)
Format: article
Language:eng
Published: 2017
Subjects:
miR's epigenetic regulation
miR-130a
miRNA
Prostate cancer
SEC23B
DEPDC1
Online Access:http://hdl.handle.net/10400.22/9335
Country:Portugal
Oai:oai:recipp.ipp.pt:10400.22/9335

Internet

http://hdl.handle.net/10400.22/9335

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