Tauroursodeoxycholic acid prevents Bax-induced membrane perturbation and cytochrome c release in isolated mitochondria

Bax is a potent pro-apoptotic member of the Bcl-2 protein family that localizes to the mitochondrial membrane during apoptosis. Tauroursodeoxycholic acid (TUDCA) modulates the apoptotic threshold, in part, by preventing Bax translocation both in vitro and

Bibliographic Details
Main Author: Rodrigues, CMP (author)
Other Authors: Sola, S (author), Sharpe, JC (author), Moura, JJG (author), Steer, CJ (author)
Format: article
Language:eng
Published: 2015
Subjects:
Biochemistry & Molecular Biology
Online Access:http://hdl.handle.net/10451/21061
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/21061

Internet

http://hdl.handle.net/10451/21061

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