Characterization and development of aqueous biphasic systems envisioning their application in the purification of nucleic acids
Non-viral vectors, such as plasmid deoxyribonucleic acid (pDNA), are gaining momentum in gene therapy. However, the pDNA manufacture still requires the development of cost-effective downstream bioprocesses, able to correspond to all requirements of regulatory agencies and to provide high quantities...
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| Format: | doctoralThesis |
| Language: | eng |
| Published: |
2022
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| Online Access: | http://hdl.handle.net/10773/30469 |
| Country: | Portugal |
| Oai: | oai:ria.ua.pt:10773/30469 |