Regulation of epithelial chloride transport by tyrosine phosphorylation

In a recent study we reported the regulation of the chloride channel CFTR (Cystic Fibrosis Transmembrane Regulator Condutance) by a novel WNK4/SYK signaling pathway regulating the amount of CFTR at the cell surface. Tyrosine kinase Syk was shown to phosphorylate CFTR and promote its removal from the...

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Bibliographic Details
Main Author: Loureiro, Cláudia (author)
Other Authors: Jordan, Peter (author)
Format: conferenceObject
Language:eng
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10400.18/3402
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/3402