Anti-inflammatory choline based ionic liquids: Insights into their lipophilicity, solubility and toxicity parametrites

The impact on in vivo efficacy and safety of two novel ionic liquids based on the association of choline with nonsteroidal anti-inflammatory drugs, ketoprofen and naproxen forming IL-APIs, was evaluated. Their lipophilicity, solubility and toxicity were assessed aiming the illustration of the pharma...

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Bibliographic Details
Main Author: Araújo, ANDRÉ (author)
Other Authors: Azevedo, Ana M.O. (author), Costa, Susana P.F. (author), Dias, Ana F.V. (author), Marques, Alexandre H.O. (author), Pinto, Paula C.A.G. (author), Bica, Katharina (author), Ressmann, Anna K. (author), Passos, Marieta L.C. (author), Reis, Salette (author), Saraiva, M. Lúcia M.F.S. (author)
Format: article
Language:eng
Published: 2018
Subjects:
Non-steroidal anti-inflammatory drugs Ionic liquids Partition coefficient Shake flask method Cytochrome c oxidase
Online Access:http://hdl.handle.net/10314/3908
Country:Portugal
Oai:oai:bdigital.ipg.pt:10314/3908

Internet

http://hdl.handle.net/10314/3908

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