Anti-inflammatory choline based ionic liquids: Insights into their lipophilicity, solubility and toxicity parametrites

The impact on in vivo efficacy and safety of two novel ionic liquids based on the association of choline with nonsteroidal anti-inflammatory drugs, ketoprofen and naproxen forming IL-APIs, was evaluated. Their lipophilicity, solubility and toxicity were assessed aiming the illustration of the pharma...

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Detalhes bibliográficos
Autor principal: Araújo, ANDRÉ (author)
Outros Autores: Azevedo, Ana M.O. (author), Costa, Susana P.F. (author), Dias, Ana F.V. (author), Marques, Alexandre H.O. (author), Pinto, Paula C.A.G. (author), Bica, Katharina (author), Ressmann, Anna K. (author), Passos, Marieta L.C. (author), Reis, Salette (author), Saraiva, M. Lúcia M.F.S. (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Non-steroidal anti-inflammatory drugs Ionic liquids Partition coefficient Shake flask method Cytochrome c oxidase
Texto completo:http://hdl.handle.net/10314/3908
País:Portugal
Oai:oai:bdigital.ipg.pt:10314/3908

Texto Completo

http://hdl.handle.net/10314/3908

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