Efficient spatially targeted gene editing using a near-infrared activatable protein-conjugated nanoparticle for brain applications

Spatial control of gene expression is critical to modulate cellular functions and deconstruct the function of individual genes in biological processes. Light-responsive gene-editing formulations have been recently developed; however, they have shown limited applicability in vivo due to poor tissue p...

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Bibliographic Details
Main Author: Rebelo, Catarina (author)
Other Authors: Reis, Tiago (author), Guedes, Joana (author), Saraiva, Cláudia (author), Rodrigues, Artur Filipe (author), Simões, Susana (author), Bernardino, Liliana (author), Peça, João (author), Pinho, Sónia L. C. (author), Ferreira, Lino (author)
Format: article
Language:eng
Published: 2022
Subjects:
Brain
Infrared Rays
Optogenetics
Proteins
Gene Editing
Nanoparticles
Online Access:http://hdl.handle.net/10316/101264
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/101264

Internet

http://hdl.handle.net/10316/101264

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