Stuck in division or passing through: What happens when cells cannot satisfy the spindle assembly checkpoint
The spindle assembly checkpoint (SAC) delays cells in mitosis when one or more kinetochore(s) cannot form a normal dynamic connection with microtubules (MTs). This occurs when spindle formation fails, or if it forms in the presence of one pole, aberrant centromeres/kinetochores, or MTs exhibiting ab...
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| Format: | article |
| Language: | eng |
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2004
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| Online Access: | http://hdl.handle.net/10216/53804 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/53804 |