Computational tools for strain optimization by tuning the optimal level of gene expression
In this work, a plug-in for the OptFlux Metabolic Engineering platform is presented, implementing methods that allow the identification of sets of genes to over/under express, relatively to their wild type levels. The optimization methods used are Simulated Annealing and Evolutionary Algorithms, wor...
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| Other Authors: | , |
| Format: | conferencePaper |
| Language: | eng |
| Published: |
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/1822/23378 |
| Country: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/23378 |