Metabolism of the Antituberculosis Drug Ethionamide

Ethionamide (ETH) is an important second-line antituberculosis drug used for the treatment of patients infected with multidrug-resistant Mycobacterium. Although ETH is a structural analogue of isoniazid (INH), both are pro-drugs that need to be activated by mycobacterial enzymes to exert their antim...

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Bibliographic Details
Main Author: Nuno Vale (author)
Other Authors: Paula Gomes (author), Helder A Santos (author)
Format: article
Language:eng
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10216/82041
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/82041