Unveiling the regulation of germinal centre responses and antibody production by follicular T cells

Germinal Centres (GCs) are the sites in secondary lymphoid tissues specialized in the selection of the effective antibody response against invading pathogens. Within GCs, B cells undergo class switch recombination (CSR) and somatic hyper-mutation (SHM) followed by the selection of high-affinity clon...

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Bibliographic Details
Main Author: Kumar, Saumya (author)
Format: doctoralThesis
Language:eng
Published: 2022
Subjects:
Células T foliculares auxiliares
Células T foliculares reguladoras
centro germinativo
transcriptómica
biologia computacional
T follicular helper cells
T follicular regulatory cells
germinal centres
transcriptomics
computational biology
Domínio/Área Científica::Ciências Médicas::Ciências da Saúde
Online Access:http://hdl.handle.net/10451/54915
Country:Portugal
Oai:oai:repositorio.ul.pt:10451/54915

Internet

http://hdl.handle.net/10451/54915

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