Gene therapy: development of a new nanocarrier system for mitochondrial gene therapy

Mitochondria are unique organelles that have their own genome, the mitochondrial DNA (mtDNA). Although quite small compared to nuclear DNA (nDNA), mutations in mtDNA are quite frequent due to the lack of protection and repair mechanisms. Per consequence, cytopathies and diseases are quite common and...

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Bibliographic Details
Main Author: Santos, João Miguel Almeida (author)
Format: masterThesis
Language:eng
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/10400.6/1627
Country:Portugal
Oai:oai:ubibliorum.ubi.pt:10400.6/1627