Disclosing the essentiality of ribose-5-phosphate isomerase B in Trypanosomatids

Ribose-5-phosphate isomerase (RPI) belongs to the non-oxidative branch of the pentose phosphate pathway, catalysing the inter-conversion of D-ribose-5-phosphate and D-ribulose-5-phosphate. Trypanosomatids encode a type B RPI, whereas humans have a structurally unrelated type A, making RPIB worthy of...

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Bibliographic Details
Main Author: Faria, J (author)
Other Authors: Loureiro, I (author), Santarém, N (author), Cecílio, P (author), Macedo-Ribeiro, S (author), Tavares, J (author), Cordeiro-da-Silva, A (author)
Format: article
Language:eng
Published: 2016
Online Access:https://repositorio-aberto.up.pt/handle/10216/118205
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/118205