Protein Kinase WNK2 has a Tumour Suppressor Role in Gliomas

Malignant glioblastoma is the most common and lethal adult brain tumour type. Recently, the promoter region of the protein kinaseWNK2 gene was found to be hypermethylated in 29 of 31 infiltrative gliomas and about 5 of 7 meningiomas. We have previously described that theexperimental depletion of WNK...

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Bibliographic Details
Main Author: Moniz, Sonia (author)
Other Authors: Martinho, Olga (author), Pinto, Filipe (author), Reis, Rui Manuel (author), Jordan, Peter (author)
Format: conferenceObject
Language:por
Published: 2012
Subjects:
Vias de Transdução de Sinal e Patologias Associadas
WNK Protein Kinases
Glioma
Tumor Suppressor
Invasion
Rac1
Online Access:http://hdl.handle.net/10400.18/1026
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/1026

Internet

http://hdl.handle.net/10400.18/1026

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