Secretory IgA and T Cells Targeting SARS-CoV-2 Spike Protein Are Transferred to the Breastmilk Upon mRNA Vaccination

In view of the scarcity of data to guide decision making, we evaluated how BNT162b2 and mRNA-1273 vaccines affect the immune response in lactating women and the protective profile of breastmilk. Compared with controls, lactating women had a higher frequency of circulating RBD memory B cells and high...

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Bibliographic Details
Main Author: Gonçalves, J (author)
Other Authors: Juliano, AM (author), Charepe, N (author), Alenquer, M (author), Athayde, D (author), Ferreira, F (author), Archer, M (author), Amorim, MJ (author), Serrano, F (author), Soares, H (author)
Format: article
Language:eng
Published: 2022
Subjects:
MAC MED MAF
Antibodies, Viral / blood
Antibodies, Viral / immunology
COVID-19 / immunology
COVID-19 / prevention & control
COVID-19 Vaccines / immunology*
Female
Humans
Immunity, Maternally-Acquired
Immunoglobulin A, Secretory / immunology*
Lactation / immunology
Memory B Cells / immunology
Milk, Human / immunology*
SARS-CoV-2 / immunology*
Spike Glycoprotein, Coronavirus / immunology*
T-Lymphocytes / immunology*
mRNA Vaccines / immunology
Vaccination
Online Access:http://hdl.handle.net/10400.17/3960
Country:Portugal
Oai:oai:repositorio.chlc.min-saude.pt:10400.17/3960

Internet

http://hdl.handle.net/10400.17/3960

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