Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

DNA methylation is an epigenetic modification of the genome involved in regulating crucial cellular processes, including transcription and chromosome stability. Advances in PacBio sequencing technologies can be used to robustly reveal methylation sites. The methylome of the Mycobacterium tuberculosi...

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Bibliographic Details
Main Author: Phelan, Jody (author)
Other Authors: De Sessions, Paola Florez (author), Tientcheu, Leopold (author), Perdigao, Joao (author), Machado, Diana (author), Hasan, Rumina (author), Hasan, Zahra (author), Bergval, Indra L. (author), Anthony, Richard (author), McNerney, Ruth (author), Antonio, Martin (author), Portugal, Isabel (author), Viveiros, Miguel (author), Campino, Susana (author), Hibberd, Martin L. (author), Clark, Taane G. (author)
Format: article
Language:eng
Published: 2021
Subjects:
Online Access:http://hdl.handle.net/10362/116703
Country:Portugal
Oai:oai:run.unl.pt:10362/116703