Methylation in Mycobacterium tuberculosis is lineage specific with associated mutations present globally

DNA methylation is an epigenetic modification of the genome involved in regulating crucial cellular processes, including transcription and chromosome stability. Advances in PacBio sequencing technologies can be used to robustly reveal methylation sites. The methylome of the Mycobacterium tuberculosi...

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Detalhes bibliográficos
Autor principal: Phelan, Jody (author)
Outros Autores: De Sessions, Paola Florez (author), Tientcheu, Leopold (author), Perdigao, Joao (author), Machado, Diana (author), Hasan, Rumina (author), Hasan, Zahra (author), Bergval, Indra L. (author), Anthony, Richard (author), McNerney, Ruth (author), Antonio, Martin (author), Portugal, Isabel (author), Viveiros, Miguel (author), Campino, Susana (author), Hibberd, Martin L. (author), Clark, Taane G. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/10362/116703
País:Portugal
Oai:oai:run.unl.pt:10362/116703