Cytotoxic effects of metal complexes of biogenic polyamines. I. Platinum(II) spermidine compounds: prediction of their antitumour activity

Cytotoxicity and cell growth inhibition studies were performed for three distinct polynuclear platinum(II) complexes of spermidine, which showed to have significant cytotoxic and antiproliferative properties on the HeLa cancer cell line. The chemical environment of the metal centres in the drugs, as...

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Detalhes bibliográficos
Autor principal: Marques, M. P. M. (author)
Outros Autores: Girão, T. (author), Lima, Maria C. Pedroso de (author), Gameiro, A. (author), Pereira, E. (author), Garcia, P. (author)
Formato: article
Idioma:eng
Publicado em: 2002
Assuntos:
Texto completo:http://hdl.handle.net/10316/3882
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/3882