OSBPL10, RXRA and lipid metabolism confer African-ancestry protection against dengue haemorrhagic fever in admixed Cubans

Ethnic groups can display differential genetic susceptibility to infectious diseases. The arthropod-born viral dengue disease is one such disease, with empirical and limited genetic evidence showing that African ancestry may be protective against the haemorrhagic phenotype. Global ancestry analysis...

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Bibliographic Details
Main Author: Sierra, B (author)
Other Authors: Triska, P (author), Soares, P (author), Garcia, G (author), Perez, AB (author), Aguirre, E (author), Oliveira, M (author), Cavadas, B (author), Regnault, B (author), Alvarez, M (author), Ruiz, D (author), Samuels, DC (author), Sakuntabhai, A (author), Pereira, L (author), Guzman, MG (author)
Format: article
Language:eng
Published: 2017
Subjects:
Genome-wide association
Liver-x-receptors
Binding proteins
Virus
Genes
Susceptibility
Infection
Admixture
Determinants
Replication
Online Access:http://hdl.handle.net/10216/109273
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/109273

Internet

http://hdl.handle.net/10216/109273

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