Mitch a rapidly evolving component of the Ndc80 kinetochore complex required for correct chromosome segregation in Drosophila

We identified an essential kinetochore protein, Mitch, from a genetic screen in D. melanogaster. Mitch localizes to the kinetochore, and its targeting is independent of microtubules (MTs) and several other known kinetochore components. Animals carrying mutations in mitch die as late third-instar lar...

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Bibliographic Details
Main Author: Williams, B (author)
Other Authors: Leung, G (author), Maiato, H (author), Wong, A (author), Li, Z (author), Williams, E (author), Kirkpatrick, C (author), Aquadro, CF (author), Rieder, CL (author), Goldberg, ML (author)
Format: article
Language:eng
Published: 2007
Subjects:
Aneuploidy
Spindle checkpoint
Chromosome congression
Mono-oriented chromosomes
Online Access:http://hdl.handle.net/10216/35043
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/35043

Internet

http://hdl.handle.net/10216/35043

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