Mitch a rapidly evolving component of the Ndc80 kinetochore complex required for correct chromosome segregation in Drosophila

We identified an essential kinetochore protein, Mitch, from a genetic screen in D. melanogaster. Mitch localizes to the kinetochore, and its targeting is independent of microtubules (MTs) and several other known kinetochore components. Animals carrying mutations in mitch die as late third-instar lar...

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Detalhes bibliográficos
Autor principal: Williams, B (author)
Outros Autores: Leung, G (author), Maiato, H (author), Wong, A (author), Li, Z (author), Williams, E (author), Kirkpatrick, C (author), Aquadro, CF (author), Rieder, CL (author), Goldberg, ML (author)
Formato: article
Idioma:eng
Publicado em: 2007
Assuntos:
Aneuploidy
Spindle checkpoint
Chromosome congression
Mono-oriented chromosomes
Texto completo:http://hdl.handle.net/10216/35043
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/35043

Texto Completo

http://hdl.handle.net/10216/35043

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