Evaluation of a gene-by-gene approach for prospective whole-genome sequencing-based surveillance of multidrug resistant Mycobacterium tuberculosis

Whole-genome sequencing (WGS) offers unprecedented resolution for tracking Mycobacterium tuberculosis transmission and antibiotic-resistance spread. Still, the establishment of standardized WGS-based pipelines and the definition of epidemiological clusters based on genetic relatedness are under disc...

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Bibliographic Details
Main Author: Macedo, Rita (author)
Other Authors: Pinto, Miguel (author), Borges, Vítor (author), Nunes, Alexandra (author), Oliveira, Olena Radomska (author), Portugal, Isabel (author), Duarte, Raquel (author), Gomes, João Paulo (author)
Format: article
Language:eng
Published: 2019
Subjects:
Genes, Bacterial
Genome, Bacterial
Genotype
Humans
Mycobacterium tuberculosis
Phylogeny
Polymorphism, Single Nucleotide
Portugal
Prospective Studies
Tuberculosis, Multidrug-Resistant
Whole Genome Sequencing
Surveillance
Gene-by-gene approach
Multidrug-resistance
Science & Technology
Online Access:http://hdl.handle.net/1822/67295
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/67295

Internet

http://hdl.handle.net/1822/67295

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