TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy

Background. The aim of our work was to replicate, in a Southern European population, the association reported in Northern populations between PTPRC locus and response to anti-tumor necrosis factor (anti-TNF) treatment in rheumatoid arthritis (RA). We also looked at associations between five RA risk...

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Bibliographic Details
Main Author: Canhão, Helena (author)
Other Authors: Rodrigues, Ana Maria (author), Santos, Maria José (author), Carmona-Fernandes, Diana (author), Bettencourt, Bruno F. (author), Cui, Jing (author), Rocha, Fabiana L. (author), Canas da Silva, José (author), Polido-Pereira, Joaquim (author), Pereira Silva, José Alberto (author), Costa, José António (author), Araujo, Domingos (author), Silva, Cândida (author), Santos, Helena (author), Duarte, Cátia (author), Cáliz, Rafael (author), Filipescu, Ileana (author), Pimentel-Santos, Fernando (author), Branco, Jaime (author), Sainz, Juan (author), Plenge, Robert M (author), Solomon, Daniel H. (author), Bruges-Armas, Jácome (author), da Silva, José António Pereira (author), Fonseca, João Eurico (author), Karlson, Elizabeth W (author)
Format: article
Language:eng
Published: 2017
Subjects:
GENOME-WIDE ASSOCIATION
ALPHA THERAPY
SUSCEPTIBILITY
HLA-DRB1
DISEASES
METHOTREXATE
POLYMORPHISM
ETANERCEPT
REMISSION
REGISTER
Immunology and Microbiology(all)
Biochemistry, Genetics and Molecular Biology(all)
Online Access:https://doi.org/10.1155/2015/490295
Country:Portugal
Oai:oai:run.unl.pt:10362/21946

Internet

https://doi.org/10.1155/2015/490295

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