The anticancer agent 3-bromopyruvate: a simple but powerful molecule taken from the lab to the bedside

At the beginning of the twenty-first century, 3-bromopyruvate (3BP), a simple alkylating chemical compound was presented to the scientific community as a potent anticancer agent, able to cause rapid toxicity to cancer cells without bystander effects on normal tissues. The altered metabolism of cance...

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Bibliographic Details
Main Author: Silva, J. Azevedo (author)
Other Authors: Queirós, O (author), Baltazar, Fátima (author), Ułaszewski, S. (author), Goffeau. A. (author), Ko, Y. H. (author), Pedersen, Peter L. (author), Preto, Ana (author), Casal, Margarida (author)
Format: article
Language:eng
Published: 2016
Subjects:
3-bromopyruvate
Monocarboxylate transporter
Cancer metabolism
Tumor microenvironment
Cancer therapy
Clinical studies
Science & Technology
Online Access:http://hdl.handle.net/1822/45108
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/45108

Internet

http://hdl.handle.net/1822/45108

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