Optimization of bacterial strains with variable-sized evolutionary algorithms

In metabolic engineering it is difficult to identify which set of genetic manipulations will result in a microbial strain that achieves a desired production goal, due to the complexity of the metabolic and regulatory cellular networks and to the lack of appropriate modeling and optimization tools. I...

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Bibliographic Details
Main Author: Rocha, Miguel (author)
Other Authors: Pinto, José P. (author), Rocha, I. (author), Ferreira, Eugénio C. (author)
Format: conferencePaper
Language:eng
Published: 2007
Subjects:
Evolutionary Algorithms
Set based representations
Variable size chromosomes
Metabolic engineering
Flux-balance analysis
Science & Technology
Online Access:https://hdl.handle.net/1822/6602
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/6602

Internet

https://hdl.handle.net/1822/6602

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