CD44 glycoprotein in cancer: A molecular conundrum hampering clinical applications

CD44 is a heavily glycosylated membrane receptor playing a key role in cell adhesion, signal transduction and cytoskeleton remodelling. It is also one of the most studied glycoproteins in cancer, frequently explored for stem cell identification, and associated with chemoresistance and metastasis. Ho...

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Detalhes bibliográficos
Autor principal: Azevedo, R (author)
Outros Autores: Gaiteiro, C (author), Peixoto, A (author), Relvas-Santos, M (author), Lima, L (author), Santos, L (author), Ferreira, JA (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Texto completo:https://hdl.handle.net/10216/126486
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/126486