Diels–Alder reactions of 3-(1H-tetrazol-5-yl)-nitrosoalkenes: synthesis of functionalized 5-(substituted)-1H-tetrazoles
A general route to 1,2-oxazines and open chain oximes bearing a 1H-tetrazolyl substituent via DielseAlder reaction of 3-(tetrazol-5-yl)-nitrosoalkenes is reported. It was also demonstrated that reduction of these adducts followed by deprotection of the tetrazolyl group give 5-(1-aminoalkyl)-1H-tetra...
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| Other Authors: | , , |
| Format: | article |
| Language: | eng |
| Published: |
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10400.1/1046 |
| Country: | Portugal |
| Oai: | oai:sapientia.ualg.pt:10400.1/1046 |
| Summary: | A general route to 1,2-oxazines and open chain oximes bearing a 1H-tetrazolyl substituent via DielseAlder reaction of 3-(tetrazol-5-yl)-nitrosoalkenes is reported. It was also demonstrated that reduction of these adducts followed by deprotection of the tetrazolyl group give 5-(1-aminoalkyl)-1H-tetrazoles, a-amino acid analogues. |
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