Synthesis of a 3-hydroxyl-free N-acetyl glucosamine disaccharide

A simple and alternative route to a versatile N-acetyl glucosamine disaccharide building block was developed, possessing a free 3-hydroxyl group. In this strategy, the 2,2,2-trichloro-ethoxy carbonyl (Troc) group was used as an amino-and 3-hydroxyl-protecting group.

Bibliographic Details
Main Author: Enugala, Ramu (author)
Other Authors: Marques, M. Manuel B. (author)
Format: article
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10362/92206
Country:Portugal
Oai:oai:run.unl.pt:10362/92206
Description
Summary:A simple and alternative route to a versatile N-acetyl glucosamine disaccharide building block was developed, possessing a free 3-hydroxyl group. In this strategy, the 2,2,2-trichloro-ethoxy carbonyl (Troc) group was used as an amino-and 3-hydroxyl-protecting group.