Insights on mycobacterium leprae efflux pumps and their implications in drug resistance and virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Detalhes bibliográficos
Autor principal: Machado, Diana (author)
Outros Autores: Lecorche, Emmanuel (author), Mougari, Faiza (author), Cambau, Emmanuelle (author), Viveiros, Miguel (author)
Formato: review
Idioma:eng
Publicado em: 2021
Assuntos:
Texto completo:http://hdl.handle.net/10362/116694
País:Portugal
Oai:oai:run.unl.pt:10362/116694