Insights on mycobacterium leprae efflux pumps and their implications in drug resistance and virulence

Drug resistance in Mycobacterium leprae is assumed to be due to genetic alterations in the drug targets and reduced cell wall permeability. However, as observed in Mycobacterium tuberculosis, drug resistance may also result from the overactivity of efflux systems, which is mostly unexplored. In this...

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Bibliographic Details
Main Author: Machado, Diana (author)
Other Authors: Lecorche, Emmanuel (author), Mougari, Faiza (author), Cambau, Emmanuelle (author), Viveiros, Miguel (author)
Format: review
Language:eng
Published: 2021
Subjects:
Antimicrobial resistance
Efflux pumps
Leprosy
Mycobacteria
Tuberculosis
Virulence
Microbiology
Microbiology (medical)
Biochemistry, Genetics and Molecular Biology (miscellaneous)
Infectious Diseases
SDG 3 - Good Health and Well-being
Online Access:http://hdl.handle.net/10362/116694
Country:Portugal
Oai:oai:run.unl.pt:10362/116694

Internet

http://hdl.handle.net/10362/116694

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