Search for killer phenotypes with potential for biological control
The aim of this work was to investigate the expression of killer phenotypes in a panel of clinical and industrial selected yeast strains. Killer activity was observed in Candida utilis, Dekkera bruxellensis, Sterigmatomyces halophilus, Stephanoascus ciferrii, Pichia holstii and Pichia jadinii - yeas...
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| Formato: | article |
| Idioma: | eng |
| Publicado em: |
2012
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| Texto completo: | http://hdl.handle.net/1822/16070 |
| País: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/16070 |
| Resumo: | The aim of this work was to investigate the expression of killer phenotypes in a panel of clinical and industrial selected yeast strains. Killer activity was observed in Candida utilis, Dekkera bruxellensis, Sterigmatomyces halophilus, Stephanoascus ciferrii, Pichia holstii and Pichia jadinii - yeasts in which killer phenotype has never been described. Two of the strains that exhibited the broadest killer spectra - Candida utilis and Dekkera bruxellensis - also displayed considerable antagonistic activity against selected Candida strains. These yeasts and/or toxins may be of potential use in the development of new antimycotic agents, considering the increase in Candida-associated opportunistic infections and the growing demand for alternative therapeutic agents. |
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