Data on metabolic profile of insulin-degrading enzyme knockout mice

Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of co...

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Bibliographic Details
Main Author: Borges, Diego O. (author)
Other Authors: Meneses, Maria João (author), Dias, Tânia R. (author), Martins, Fátima O. (author), Oliveira, Pedro F. (author), Alves, Marco G. (author), Macedo, M. Paula (author)
Format: article
Language:eng
Published: 2019
Subjects:
General
Online Access:https://doi.org/10.1016/j.dib.2019.104023
Country:Portugal
Oai:oai:run.unl.pt:10362/75566
Description
Summary:Insulin-degrading enzyme (IDE) degrades and inactivates bioactive peptides such as insulin. As insulin is a master regulator of glucose homeostasis, lack of IDE is expected to have a profound impact on both insulin and glucose levels. This article shares data on glucose and insulin homeostasis of control, heterozygous and knockout mice for Ide after 18 weeks of a normal chow diet. This data article is related to a research article entitled “Knockout of insulin-degrading enzyme leads to mice testicular morphological changes and impaired sperm quality” (Meneses et al., 2019).

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