Iron-citrate can induce cell senescent phenotype in human fibroblasts in vitro
After a number of replications, human diploid fibroblasts (HDFs) in culture lose the ability to divide, become insensitive to further proliferation and enter a state of replicative senescence (RS). Subcytotoxic doses of several stressful agents such as hydrogen peroxide, tertbutylhydroperoxide or et...
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| Format: | article |
| Language: | eng |
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2009
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| Online Access: | https://repositorio-aberto.up.pt/handle/10216/101664 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/101664 |