Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax

Proteins of the Bcl-2 protein family, including pro-apoptotic Bax and anti-apoptotic Bcl-xL, are critical for mitochondrial-mediated apoptosis regulation. Since yeast lacks obvious orthologs of Bcl-2 family members, heterologous expression of these proteins has been used to investigate their molecul...

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Bibliographic Details
Main Author: Guedes, Joana P. (author)
Other Authors: Baptista, Vitória (author), Cátia S. Pereira (author), Sousa, Maria João (author), Manon, Stéphen (author), Chaves, Susana R. (author), Côrte-Real, Manuela (author)
Format: article
Language:eng
Published: 2022
Subjects:
Acetic acid
Apoptosis
Bax
Bcl-2 family proteins
Heterologous expression
Yeast
Science & Technology
Online Access:https://hdl.handle.net/1822/77167
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/77167

Internet

https://hdl.handle.net/1822/77167

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