SMAD pathway mediation of BDNF and TGFβ2 regulation of proliferation and differentiation of hippocampal granule neurons

Hippocampal granule cells self-renew throughout life, whereas their cerebellar counterparts become post-mitotic during early postnatal development, suggesting that locally acting, tissue-specific factors may regulate the proliferative potential of each cell type. Confirming this, we show that condit...

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Bibliographic Details
Main Author: Lu, J. (author)
Other Authors: Wu, Y. (author), Sousa, Nuno (author), Almeida, O. F. X. (author)
Format: article
Language:eng
Published: 2005
Subjects:
Neurogenesis
Apoptosis
Neuronal differentiation
Hippocampus
Cerebellum
BDNF
TGFβ2
SMAD
Rat
TGF beta 2
Science & Technology
Online Access:http://hdl.handle.net/1822/5190
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/5190

Internet

http://hdl.handle.net/1822/5190

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