Novel polymorphisms in plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance

Chemotherapy is a critical component of malaria control. However, the most deadly malaria pathogen, Plasmodium falciparum, has repeatedly mounted resistance against a series of antimalarial drugs used in the last decades. Southeast Asia is an epicenter of emerging antimalarial drug resistance, inclu...

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Bibliographic Details
Main Author: Veiga, Maria Isabel (author)
Other Authors: Pousão-Ferreira, Pedro (author), Jornhagen, Louise (author), Malmberg, Maja (author), Kone, Aminatou (author), Schmidt, Berit Aydin (author), Petzold, Max (author), Bjorkman, Anders (author), Nosten, Francois (author), Gil, José Pedro (author)
Format: article
Language:eng
Published: 2018
Subjects:
Pfmdr1 Copy Number
In-Vivo Selection
Artemether-Lumefantrine
Substrate-Specificity
Artemisinin Resistance
Chloroquine Resistance
Mefloquine Resistance
Combination Therapy
Malaria Parasite
Amino-Acids
Online Access:http://hdl.handle.net/10400.1/11741
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11741

Internet

http://hdl.handle.net/10400.1/11741

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