Association of albumin or protamine to lipoplexes: enhancement of transfection and resistance to serum

The successful application of gene therapy depends on the availability of carriers to efficiently deliver genetic material into target cells. Such efficacy is strongly related to key parameters including serum resistance and protection of DNA.The complexes were tested in terms of their biological ac...

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Bibliographic Details
Main Author: Faneca, H. (author)
Other Authors: Simões, S. (author), Lima, M. C. Pedroso de (author)
Format: article
Language:eng
Published: 2004
Online Access:http://hdl.handle.net/10316/8361
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8361