Synthesis of N-alkyl-C α, α-dimethylglycine derivatives

The application of trialkyloxonium tetrafluoroborates for N-alkylation of the nonnatural amino acid Cα, α-dimethylglycine is described. Several methyl esters of dimethylglycine protected with different amine protecting groups were subject to N-ethylation or N-methylation with triethyloxonium tetrafl...

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Bibliographic Details
Main Author: Monteiro, Luís S. (author)
Other Authors: Pereira-Lima, Sílvia M. M. A. (author), Pereira, Sofia (author), Machado, João N (author)
Format: article
Language:eng
Published: 2014
Subjects:
Online Access:http://hdl.handle.net/1822/48102
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/48102