uORF-mediated translational regulation of the human PERK mRNA

Upstream open reading frames (uORFs) are cis-acting elements located within the 5’ leader sequence (5’UTR) of transcripts, which can regulate translation of the correspondent main open reading frame (mORF). During endoplasmic reticulum (ER) stress, the accumulation of unfolded proteins activates the...

ver descrição completa

Detalhes bibliográficos
Autor principal: Fernandes, Rafael (author)
Outros Autores: Lopes, Pedro (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2020
Assuntos:
Texto completo:http://hdl.handle.net/10400.18/7467
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7467