uORF-mediated translational regulation of the human PERK mRNA
Upstream open reading frames (uORFs) are cis-acting elements located within the 5’ leader sequence (5’UTR) of transcripts, which can regulate translation of the correspondent main open reading frame (mORF). During endoplasmic reticulum (ER) stress, the accumulation of unfolded proteins activates the...
Main Author: | |
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Other Authors: | , |
Format: | conferenceObject |
Language: | eng |
Published: |
2020
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Subjects: | |
Online Access: | http://hdl.handle.net/10400.18/7467 |
Country: | Portugal |
Oai: | oai:repositorio.insa.pt:10400.18/7467 |