uORF-mediated translational regulation of the human PERK mRNA

Upstream open reading frames (uORFs) are cis-acting elements located within the 5’ leader sequence (5’UTR) of transcripts, which can regulate translation of the correspondent main open reading frame (mORF). During endoplasmic reticulum (ER) stress, the accumulation of unfolded proteins activates the...

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Bibliographic Details
Main Author: Fernandes, Rafael (author)
Other Authors: Lopes, Pedro (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.18/7467
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/7467