Development and characterization of PLGA nanoparticles containing 1,3-dihydroxy-2-methylxanthone with improved antitumor activity on a human breast cancer cell line

Interest on xanthones has been growing considerably due to their broad spectrum of biological activities. 1,3-Dihydroxy-2-methylxanthone (DHMXAN) showed a significant inhibitory effect on the growth of MCF-7 cancer cells. DHMXAN-loaded nanosphere and nanocapsule formulations were prepared by the sol...

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Bibliographic Details
Main Author: Maribel, T (author)
Other Authors: Pedro, M (author), Nascimento, MSJ (author), Pinto, MMM (author), Barbosa, C.M. (author)
Format: article
Language:eng
Published: 2019
Online Access:https://hdl.handle.net/10216/127459
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/127459