Genetically-determined hyperfunction of the S100B/RAGE axis is a risk factor for aspergillosis in stem cell transplant recipients

Invasive aspergillosis (IA) is a major threat to the successful outcome of hematopoietic stem cell transplantation (HSCT), although individual risk varies considerably. Recent evidence has established a pivotal role for a danger sensing mechanism implicating the S100B/receptor for advanced glycation...

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Bibliographic Details
Main Author: Cunha, Cristina (author)
Other Authors: Giovannini, Gloria (author), Pierini, Antonio (author), Bell, Alain S. (author), Sorci, Guglielmo (author), Riuzzi, Francesca (author), Donato, Rosario (author), Rodrigues, Fernando José dos Santos (author), Velardi, Andrea (author), Aversa, Franco (author), Romani, Luigina (author), Carvalho, Agostinho (author)
Format: article
Language:eng
Published: 2011
Subjects:
Hematopoietic stem cell transplantation
Single nucleotide polymorphism
Invasive aspergillosis
S100B
RAGE
Inflammation
Science & Technology
Online Access:http://hdl.handle.net/1822/18634
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/18634

Internet

http://hdl.handle.net/1822/18634

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