Cytosolic and mitochondrial ROS in staurosporine-induced retinal cell apoptosis

In this study, we investigated the involvement of reactive oxygen species (ROS) and calcium in staurosporine (STS)-induced apoptosis in cultured retinal neurons, under conditions of maintained membrane integrity. The antioxidants idebenone (IDB), glutathione-ethylester (GSH/EE), trolox, and Mn(III)t...

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Bibliographic Details
Main Author: Gil, Joana (author)
Other Authors: Almeida, Sandra (author), Oliveira, Catarina R. (author), Rego, A. Cristina (author)
Format: article
Language:eng
Published: 2003
Subjects:
Apoptosis
Antioxidants
Calcium
Caspase-3
Mitochondria
Reactive oxygen species
Retinal cells
Staurosporine
Free radicals
Online Access:http://hdl.handle.net/10316/4797
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/4797

Internet

http://hdl.handle.net/10316/4797

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