Bonelike/PLGA hybrid materials for bone regeneration: in vivo evaluation

The biocompatibility and osteoconductive potential of Bonelike and Bonelike /PLGA hybrid materials were evaluated through subcutaneous and tibiae implantations for a 4 week period. Qualitative histology was performed to evaluate new bone formation and characterise bone-implant interface and results...

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Bibliographic Details
Main Author: Oliveira, Joaquim M. (author)
Other Authors: Lopes, M. A. (author), Kawai, T. (author), Ohtsuki, C. (author), Santos, J. D. (author), Afonso, A. (author)
Format: conferencePaper
Language:eng
Published: 2004
Subjects:
Bonelike
Histological studies
Hybrid materials
In vivo
PLGA
Online Access:http://hdl.handle.net/1822/17472
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/17472
Description
Summary:The biocompatibility and osteoconductive potential of Bonelike and Bonelike /PLGA hybrid materials were evaluated through subcutaneous and tibiae implantations for a 4 week period. Qualitative histology was performed to evaluate new bone formation and characterise bone-implant interface and results showed that Bonelike /PLGA hybrid materials promote extensive bone growth. After the 4 week implantation period, Bonelike resorption was recognized, which may be due to the presence of resorbable and -tricalcium phosphate phases.

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