High lipoprotein(a) cholesterol in patients with familial hypercholesterolemia

Aim: Familial Hypercholesterolemia (FH) patients have an increased cardiovascular risk due to high TC or LDL-C levels. Lp(a) chemical structure is similar to LDL and elevated Lp(a) is considered an independent risk factor for cardiovascular disease (CVD). Recently, it has been described that in pati...

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Bibliographic Details
Main Author: Medeiros, A.M. (author)
Other Authors: Alves, A.C. (author), Bourbon, M. (author)
Format: conferenceObject
Language:eng
Published: 2020
Subjects:
Online Access:http://hdl.handle.net/10400.18/6657
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/6657
Description
Summary:Aim: Familial Hypercholesterolemia (FH) patients have an increased cardiovascular risk due to high TC or LDL-C levels. Lp(a) chemical structure is similar to LDL and elevated Lp(a) is considered an independent risk factor for cardiovascular disease (CVD). Recently, it has been described that in patients with high Lp(a), the Lp(a)-C can contribute up to 25% to 50% of all LDL-C. In the present work we aim to determine if elevated Lp(a) concentrations can contribute to clinical phenotype of FH.