The interaction between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and rapidly degrades mRNAs containing premature termination codons (PTCs). Although NMD has been intensively studied, it is still poorly understood how NMD discriminates between PTCs and normal stop codons. The unified mode...

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Bibliographic Details
Main Author: Onofre, Cláudia (author)
Other Authors: Menezes, Juliane (author), Peixeiro, Isabel (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2025
Subjects:
Genómica Funcional e Estrutural
Expressão Génica
Degradação do mRNA
Síntese Proteica
Nonsense-mediated mRNA Decay
Online Access:http://hdl.handle.net/10400.18/4475
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4475

Internet

http://hdl.handle.net/10400.18/4475

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