Effects of Carvedilol on Isolated Heart Mitochondria: Evidence for a Protonophoretic Mechanism

Carvedilol ({1-[carbazolyl-(4)-oxy]-3-[2-methoxyphenoxyethyl)amino]-propanol-(2)}) is a novel compound used in clinical practice for the treatment of congestive heart failure, mild to moderate hypertension, and myocardial infarction. Carvedilol was also shown to protect cardiac mitochondria from oxi...

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Bibliographic Details
Main Author: Oliveira, Paulo J. (author)
Other Authors: Marques, M. Paula M. (author), Carvalho, Luís A. E. Batista de (author), Moreno, A. J. M. (author)
Format: article
Language:eng
Published: 2000
Subjects:
Animals
Antioxidants
Carbazoles
Electron Transport
Male
Membrane Potentials
Mitochondria, Heart
Mitochondrial Swelling
Oxygen Consumption
Propanolamines
Rats
Rats, Wistar
Online Access:http://hdl.handle.net/10316/5441
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5441

Internet

http://hdl.handle.net/10316/5441

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