Gardnerella vaginalis enhances Atopobium vaginae viability in vitro

Background: Bacterial vaginosis (BV) is a clinical condition characterized by a dramatic shift in the vaginal microflora from the beneficial lactobacilli to a polymicrobial flora, consisting of strictly and facultatively anaerobic bacteria. It is noteworthy that a hallmark of BV is the presence of a...

ver descrição completa

Detalhes bibliográficos
Autor principal: Castro, Joana (author)
Outros Autores: Rosca, A. (author), Piet Cools (author), Mario Vaneechoutte (author), Cerca, Nuno (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2019
Assuntos:
Texto completo:http://hdl.handle.net/1822/62724
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/62724
Descrição
Resumo:Background: Bacterial vaginosis (BV) is a clinical condition characterized by a dramatic shift in the vaginal microflora from the beneficial lactobacilli to a polymicrobial flora, consisting of strictly and facultatively anaerobic bacteria. It is noteworthy that a hallmark of BV is the presence of a highly structured polymicrobial biofilm on the vaginal epithelium, presumably initiated by a facultative anaerobe, Gardnerella vaginalis, which then become a scaffold for other species to adhere. While not much is known about multi- species interactions within BV biofilms, Atopobium vaginae is often associated with G. vaginalis biofilms and is rarely detected without G. vaginalis.