Evaluating the integration of proteomic data for the prediction of intracellular fluxes after knockout experiments

So far, few large scale kinetic models of metabolic networks have been successfully constructed. The main reasons for this are not only the associated mathematical complexity, but also the large number of unknown kinetic parameters required in the rate equations to define the system. In contrast to...

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Bibliographic Details
Main Author: Costa, Rafael S. (author)
Other Authors: Machado, C. D. (author), Ferreira, Eugénio C. (author), Rocha, I. (author)
Format: conferencePaper
Language:eng
Published: 2010
Subjects:
Online Access:https://hdl.handle.net/1822/22315
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/22315