Carvedilol Protects against Doxorubicin-Induced Mitochondrial Cardiomyopathy

Several cytopathic mechanisms have been suggested to mediate the dose-limiting cumulative and irreversible cardiomyopathy caused by doxorubicin. Recent evidence indicates that oxidative stress and mitochondrial dysfunction are key factors in the pathogenic process. The objective of this investigatio...

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Bibliographic Details
Main Author: Santos, D. L. (author)
Other Authors: Moreno, A. J. M. (author), Leino, R. L. (author), Froberg, M. K. (author), Wallace, K. B. (author)
Format: article
Language:eng
Published: 2002
Subjects:
Adriamycin
Adrenergic
Toxicity
Mitochondria
Online Access:http://hdl.handle.net/10316/5412
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5412

Internet

http://hdl.handle.net/10316/5412

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